Overview
5-Bromo valeric acid is an organic compound used extensively in organic synthesis, pharmaceuticals, and as an intermediate in various chemical processes. Known for its reactivity due to the presence of both a bromine atom and a carboxylic acid group, this compound plays a significant role in creating more complex molecules. This post provides a detailed overview of 5-Bromo valeric acid, including its chemical properties, applications, and safety measures.
Description
5-Bromo valeric acid is a white to off-white crystalline powder. It is an aliphatic bromocarboxylic acid, making it highly reactive and useful in a variety of synthetic applications. The presence of both bromine and carboxylic acid functional groups allows it to participate in a wide range of chemical reactions.
Product Information
- IUPAC Name: 5-Bromopentanoic acid
- Common Name: 5-Bromo valeric acid
- CAS Number: 2067-33-6
- Molecular Formula: C₅H₉BrO₂
- Molecular Weight: 181.03 g/mol
- Appearance: White to off-white crystalline powder
- Melting Point: 40-44°C
- Boiling Point: 240°C (at 760 mmHg)
- Solubility: Soluble in water, ethanol, and ether
Applications
- Organic Synthesis
- 5-Bromo valeric acid is widely used in organic synthesis for the preparation of more complex molecules. It serves as a precursor to various chemical compounds.
- Pharmaceuticals
- Used as an intermediate in the synthesis of pharmaceuticals, contributing to the production of active pharmaceutical ingredients (APIs).
- Agrochemicals
- Employed in the synthesis of agrochemicals, including herbicides and pesticides.
- Chemical Research
- Utilized in academic and industrial research for studying reaction mechanisms and developing new synthetic methodologies.
- Polymer Chemistry
- Acts as a building block in the synthesis of specialized polymers and materials.
Physicochemical Information
- Molecular Formula: C₅H₉BrO₂
- Molecular Weight: 181.03 g/mol
- Appearance: White to off-white crystalline powder
- Melting Point: 40-44°C
- Boiling Point: 240°C (at 760 mmHg)
- Solubility: Soluble in water, ethanol, and ether
Safety Information According to GHS
- Hazard Statements:
- H302: Harmful if swallowed
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
- Precautionary Statements:
- P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
- P280: Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
- P302+P352: IF ON SKIN: Wash with plenty of soap and water.
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Safety Information
- Hazards: 5-Bromo valeric acid can cause irritation to the skin, eyes, and respiratory system. It is harmful if swallowed and should be handled with care to avoid exposure.
- Protective Measures: Use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work with 5-Bromo valeric acid should be conducted in a well-ventilated area, preferably in a fume hood.
- Storage: Store in tightly sealed containers, away from light, moisture, and incompatible substances.
Storage and Shipping Information
- Storage Conditions: Store in a cool, dry place in tightly sealed containers. Protect from light and moisture.
- Shipping Information: Transport according to local regulations. Ensure containers are secure and upright during transit to prevent leaks.
Transport Information
- UN Number: Not classified as hazardous for transport
- Hazard Class: Not classified
- Packing Group: Not classified
- Proper Shipping Name: Not classified
Specifications
- Purity: Typically >98%
- Appearance: White to off-white crystalline powder
- Melting Point: 40-44°C
- Boiling Point: 240°C (at 760 mmHg)
Related Products & Applications
- 5-Bromopentanol: Used in similar applications for organic synthesis and pharmaceutical intermediates.
- Valeric Acid: Employed in the production of perfumes, flavors, and pharmaceuticals.
- Brominated Compounds: Various compounds used in organic synthesis and as intermediates in chemical manufacturing.
- Carboxylic Acids: A wide range of carboxylic acids used in the synthesis of polymers, pharmaceuticals, and agrochemicals.
By understanding the chemical properties, applications, and safety measures of 5-Bromo valeric acid, researchers and industry professionals can effectively utilize this versatile compound in various scientific and industrial processes while ensuring safety and regulatory compliance.