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5-Bromovaleric Acid

5-Bromo Valeric Acid

Overview

5-Bromovaleric Acid is an organic compound used extensively in organic synthesis, pharmaceuticals, and as an intermediate in various chemical processes. Known for its reactivity due to the presence of a bromine atom and a carboxylic acid group, this compound plays a significant role in creating more complex molecules. This post provides a detailed overview of 5-Bromovaleric Acid, including its chemical properties, applications, and safety measures.


Description

5-Bromovaleric Acid is a white to off-white crystalline powder. It is an aliphatic monocarboxylic acid that is highly reactive and helpful in various synthetic applications. Bromine and carboxylic acid functional groups allow it to participate in a wide range of chemical reactions.


Product Information

  • IUPAC Name: 5-Bromopentanoic acid
  • Common Name: 5-Bromovaleric Acid
  • CAS Number: 2067-33-6
  • Molecular Formula: C₅H₉BrO₂
  • Molecular Weight: 181.03 g/mol
  • Appearance: White to off-white crystalline powder
  • Melting Point: 40-44°C
  • Boiling Point: 240°C (at 760 mmHg)
  • Solubility: Soluble in water, ethanol, and ether

Applications

  1. Organic Synthesis
    • 5-Bromovaleric Acid is widely used in organic synthesis to prepare more complex molecules. It serves as a precursor to various chemical compounds.
  2. Pharmaceuticals
    • Used as an intermediate in synthesizing pharmaceuticals, contributing to producing active pharmaceutical ingredients (APIs).
  3. Agrochemicals
    • Employed in the synthesis of agrochemicals, including herbicides and pesticides.
  4. Chemical Research
    • Utilized in academic and industrial research to study reaction mechanisms and develop new synthetic methodologies.
  5. Polymer Chemistry
    • Acts as a building block in the synthesis of specialized polymers and materials.

Physicochemical Information

  • Molecular Formula: C₅H₉BrO₂
  • Molecular Weight: 181.03 g/mol
  • Appearance: White to off-white crystalline powder
  • Melting Point: 40-44°C
  • Boiling Point: 240°C (at 760 mmHg)
  • Solubility: Soluble in water, ethanol, and ether

Safety Information According to GHS

  • Hazard Statements:
    • H302: Harmful if swallowed
    • H315: Causes skin irritation
    • H319: Causes severe eye irritation
    • H335: May cause respiratory irritation
  • Precautionary Statements:
    • P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
    • P280: Wear protective gloves/protective clothing/eye protection/face protection.
    • P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
    • P302+P352: IF ON SKIN: Wash with plenty of soap and water.
    • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. If contact lenses are present and easy to remove, continue rinsing.

Safety Information

  • Hazards: 5-Bromovaleric Acid can irritate the skin, eyes, and respiratory system. It is harmful if swallowed and should be handled carefully to avoid exposure.
  • Protective Measures: Wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and lab coats. Work with 5-bromovaleric Acid should be conducted in a well-ventilated area, preferably in a fume hood.
  • Storage: Store in tightly sealed containers, away from light, moisture, and incompatible substances.

Storage and Shipping Information

  • Storage Conditions: Store in tightly sealed containers in a cool, dry place. Protect from light and moisture.
  • Shipping Information: Transport according to local regulations. Ensure containers are secure and upright during transit to prevent leaks.

Transport Information

  • UN Number: Not classified as hazardous for transport
  • Hazard Class: Not classified
  • Packing Group: Not classified
  • Proper Shipping Name: Not classified

Specifications

  • Purity: Typically >98%
  • Appearance: White to off-white crystalline powder
  • Melting Point: 40-44°C
  • Boiling Point: 240°C (at 760 mmHg)

Related Products & Applications

  • 5-Bromopentanol: Used in similar applications for organic synthesis and pharmaceutical intermediates.
  • Valeric Acid: Employed in producing perfumes, flavors, and pharmaceuticals.
  • Brominated Compounds: Various compounds are used in organic synthesis and as intermediates in chemical manufacturing.
  • Carboxylic Acids: A wide range of carboxylic acids used in synthesizing polymers, pharmaceuticals, and agrochemicals.

By understanding the chemical properties, applications, and safety measures of 5-Bromovaleric Acid, researchers and industry professionals can effectively utilize this versatile compound in various scientific and industrial processes while ensuring safety and regulatory compliance.

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