Overview
Methyl cyclopropane carboxylate is an organic compound used in various chemical syntheses and industrial applications. Known for its cyclopropane ring and ester functional group, this compound is a valuable intermediate in the production of pharmaceuticals, agrochemicals, and fine chemicals. This post provides a detailed overview of methyl cyclopropane carboxylate, including its chemical properties, applications, and safety measures.
Description
Methyl cyclopropane carboxylate is a colorless liquid with a characteristic ester odor. It features a cyclopropane ring bonded to a carboxylate ester group, making it a versatile reagent in organic synthesis.
Product Information
- IUPAC Name: Methyl cyclopropane-1-carboxylate
- Common Name: Methyl cyclopropane carboxylate
- CAS Number: 2868-37-3
- Molecular Formula: C₅H₈O₂
- Molecular Weight: 100.12 g/mol
- Chemical Structure:
- Appearance: Colorless liquid
- Boiling Point: 107-109°C
- Density: 1.004 g/cm³
- Solubility: Soluble in organic solvents such as ethanol, ether, and chloroform; slightly soluble in water
Applications
- Organic Synthesis
- Methyl cyclopropane carboxylate is widely used as an intermediate in organic synthesis. It is involved in the preparation of various cyclopropane derivatives, which are important in the development of pharmaceuticals and fine chemicals.
- Pharmaceuticals
- This compound serves as a building block in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
- Agrochemicals
- Used in the synthesis of agrochemicals, including insecticides, herbicides, and fungicides, contributing to improved agricultural productivity.
- Chemical Research
- Employed in academic and industrial research for studying reaction mechanisms, developing new synthetic methodologies, and producing novel cyclopropane compounds.
Physicochemical Information
- Molecular Formula: C₅H₈O₂
- Molecular Weight: 100.12 g/mol
- Appearance: Colorless liquid
- Boiling Point: 107-109°C
- Density: 1.004 g/cm³
- Solubility: Soluble in organic solvents; slightly soluble in water
Safety Information According to GHS
- Hazard Statements:
- H226: Flammable liquid and vapor
- H302: Harmful if swallowed
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
- Precautionary Statements:
- P210: Keep away from heat, hot surfaces, sparks, open flames, and other ignition sources. No smoking.
- P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
- P280: Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
- P302+P352: IF ON SKIN: Wash with plenty of soap and water.
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Safety Information
- Hazards: Methyl cyclopropane carboxylate is flammable and can cause irritation to the skin, eyes, and respiratory system. Handle with care to avoid exposure.
- Protective Measures: Use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work with methyl cyclopropane carboxylate should be conducted in a well-ventilated area, preferably in a fume hood.
- Storage: Store in tightly sealed containers, away from light, heat, and incompatible substances.
Storage and Shipping Information
- Storage Conditions: Store in a cool, dry place in tightly sealed containers. Protect from light, heat, and moisture.
- Shipping Information: Transport according to local regulations. Ensure containers are secure and upright during transit to prevent leaks.
Transport Information
- UN Number: 3272
- Hazard Class: 3 (Flammable liquids)
- Packing Group: III
- Proper Shipping Name: Esters, n.o.s. (contains Methyl cyclopropane carboxylate)
Specifications
- Purity: Typically >98%
- Appearance: Colorless liquid
- Boiling Point: 107-109°C
- Density: 1.004 g/cm³
Related Products & Applications
By understanding the chemical properties, applications, and safety measures of methylcyclopropane carboxylate, researchers and industry professionals can effectively utilize this versatile compound in various scientific and industrial processes while ensuring safety and regulatory compliance.