Overview
N,O-Dimethylhydroxylamine HCL, commonly abbreviated as DMHA·HCl, is a versatile reagent in organic synthesis, particularly used in the formation of oximes and oxime ethers. This post explores the chemical properties, applications, and safety measures associated with N,O-Dimethylhydroxylamine hydrochloride, providing a thorough overview for researchers and industry professionals.
Description
N,O-Dimethylhydroxylamine hydrochloride is a white to off-white crystalline powder. It is a stable compound that finds use in various synthetic applications, notably in the preparation of intermediates for pharmaceuticals and agrochemicals.
Product Information
- IUPAC Name: N-Methoxy-N-methylmethanamine HCL
- Common Name: N,O-Dimethylhydroxylamine HCL(DMHA·HCl)
- CAS Number: 6638-79-5
- Molecular Formula: C₂H₈ClNO
- Molecular Weight: 97.54 g/mol
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in water and various organic solvents such as methanol and ethanol
Applications
- Organic Synthesis
- DMHA·HCl is used in the synthesis of oximes and oxime ethers, which are valuable intermediates in the production of pharmaceuticals and agrochemicals.
- Pharmaceutical Intermediates
- It is employed in the preparation of intermediates for various pharmaceutical compounds, enhancing the efficiency of synthetic routes.
- Agrochemical Synthesis
- Used in the production of agrochemicals, DMHA·HCl helps in forming key intermediates necessary for active ingredients.
- Chemical Research
- It is utilized in research laboratories for studying new synthetic pathways and developing novel compounds.
Physicochemical Information
- Molecular Formula: C₂H₈ClNO
- Molecular Weight: 97.54 g/mol
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in water and organic solvents like methanol and ethanol
Safety Information According to GHS
- Hazard Statements:
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
- Precautionary Statements:
- P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
- P280: Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352: IF ON SKIN: Wash with plenty of soap and water.
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Safety Information
- Hazards: DMHA·HCl can cause irritation to the skin, eyes, and respiratory system. Handle with care to avoid exposure.
- Protective Measures: Use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work with DMHA·HCl should be conducted in a well-ventilated area, preferably in a fume hood.
- Storage: Store in tightly sealed containers, away from moisture and incompatible substances.
Storage and Shipping Information
- Storage Conditions: Store in a cool, dry place in tightly sealed containers. Protect from moisture and incompatible substances.
- Shipping Information: Transport according to local regulations. Ensure containers are secure and upright during transit to prevent leaks.
Transport Information
- UN Number: Not classified as hazardous for transport
- Hazard Class: Not classified
- Packing Group: Not classified
- Proper Shipping Name: Not classified
Specifications
- Purity: Typically >98%
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in water, methanol, and ethanol
Related Products & Applications
By understanding the chemical properties, applications, and safety measures of N,O-Dimethylhydroxylamine hydrochloride, researchers and industry professionals can effectively utilize this versatile reagent in various scientific and industrial processes while ensuring safety and regulatory compliance.