Overview
Veratric acid is an organic compound commonly used in the synthesis of pharmaceuticals and agrochemicals and as an intermediate in various chemical processes. Known for its aromatic properties and potential antioxidant activity, this compound plays a significant role in both industrial applications and academic research. This post provides a detailed overview of veratric acid, including its chemical properties, applications, and safety measures.
Description
Veratric acid is a white crystalline powder that is a dimethoxy derivative of benzoic acid. It is also known by its IUPAC name, 3,4-dimethoxybenzoic acid. Veratric acid is found naturally in various plants and has been studied for its potential biological activities.
Product Information
- IUPAC Name: 3,4-Dimethoxybenzoic acid
- Common Name: Veratric acid
- CAS Number: 93-07-2
- Molecular Formula: C₉H₁₀O₄
- Molecular Weight: 182.17 g/mol
- Chemical Structure:
- Appearance: White crystalline powder
- Melting Point: 180-182°C
- Solubility: Soluble in hot water, ethanol, methanol, and ether; slightly soluble in cold water
Applications
- Pharmaceuticals
- Veratric acid is used as an intermediate in the synthesis of various pharmaceutical compounds, including anti-inflammatory and anticancer agents.
- Agrochemicals
- It serves as a precursor in the production of agrochemicals, contributing to improved agricultural productivity.
- Organic Synthesis
- Widely utilized in organic synthesis for the preparation of aromatic compounds, dyes, and fragrances due to its reactivity and aromatic properties.
- Research and Development
- Employed in academic and industrial research for studying reaction mechanisms and developing new synthetic methodologies.
- Natural Product Studies
- Investigated for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties.
Physicochemical Information
- Molecular Formula: C₉H₁₀O₄
- Molecular Weight: 182.17 g/mol
- Appearance: White crystalline powder
- Melting Point: 180-182°C
- Solubility: Soluble in hot water, ethanol, methanol, and ether; slightly soluble in cold water
Safety Information According to GHS
- Hazard Statements:
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
- Precautionary Statements:
- P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
- P280: Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352: IF ON SKIN: Wash with plenty of soap and water.
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Safety Information
- Hazards: Veratric acid can cause irritation to the skin, eyes, and respiratory system. Handle with care to avoid exposure.
- Protective Measures: Use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work with veratric acid should be conducted in a well-ventilated area, preferably in a fume hood.
- Storage: Store in tightly sealed containers, away from light, moisture, and incompatible substances.
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Storage and Shipping Information
- Storage Conditions: Store in a cool, dry place in tightly sealed containers. Protect from light and moisture.
- Shipping Information: Transport according to local regulations. Ensure containers are secure and upright during transit to prevent leaks.
Transport Information
- UN Number: Not classified as hazardous for transport
- Hazard Class: Not classified
- Packing Group: Not classified
- Proper Shipping Name: Not classified
Specifications
- Purity: Typically >98%
- Appearance: White crystalline powder
- Melting Point: 180-182°C
Related Products & Applications
- Vanillic Acid: Used in similar applications for organic synthesis and pharmaceutical intermediates.
- Syringic Acid: Employed in the production of antioxidants and antimicrobial agents.
- Gallic Acid: Known for its antioxidant properties and used in pharmaceuticals and food additives.
- Ferulic acid has been widely studied for its potential health benefits and is used in the food and cosmetic industries.
By understanding the chemical properties, applications, and safety measures of veratric acid, researchers and industry professionals can effectively utilize this versatile compound in various scientific and industrial processes while ensuring safety and regulatory compliance.