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Safety and Handling of Veratric Acid: Best Practices in the Laboratory

Chemical Name: Veratric Acid
Molecular Formula: C9H10O4
CAS Number: 93-07-2
Molecular Weight: 182.17 g/mol
Appearance: White crystalline powder
Melting Point: 178-181°C
Solubility: Soluble in hot water, ethanol, and ether; sparingly soluble in cold water

Table of Contents

SectionDetails
1. General InformationIntroduction to Veratric Acid, including its structure and common uses
2. Chemical PropertiesOverview of key chemical properties such as molecular weight, melting point, and solubility
3. ApplicationsDetailed discussion of Veratric Acid’s uses in pharmaceuticals, organic synthesis, and other industries
4. Synthesis and DerivativesInformation on the synthesis process and its derivatives in chemical research
5. Safety and HandlingGuidelines for the safe handling and storage of Veratric Acid
6. Safety DataHazard classifications, pictograms, and precautionary statements
7. Research and StudiesSummary of recent research focused on Veratric Acid and its applications in various fields

1. General Information

Veratric Acid, also known as 3,4-Dimethoxybenzoic Acid, is a naturally occurring phenolic acid found in various plants. It is structurally characterized by two methoxy groups attached to the benzene ring at the 3rd and 4th positions, making it a dimethoxy derivative of benzoic acid. This compound is widely used in the pharmaceutical industry due to its potential antioxidant and anti-inflammatory properties. Additionally, Veratric Acid serves as a valuable intermediate in the synthesis of other organic compounds.

Safety and Handling of Veratric Acid: Best Practices in the Laboratory

2. Chemical Properties

  • Molecular Formula: C9H10O4
  • Molecular Weight: 182.17 g/mol
  • CAS Number: 93-07-2
  • Appearance: White crystalline powder
  • Melting Point: 178-181°C
  • Solubility: Soluble in hot water, ethanol, and ether; sparingly soluble in cold water

Veratric Acid’s chemical properties, particularly its solubility and stability, make it suitable for use in a variety of chemical reactions, especially where a stable phenolic acid is required.

3. Applications

Veratric Acid has several important applications:

  • Pharmaceutical Industry: It is utilized in the synthesis of various pharmaceuticals, particularly those with antioxidant properties. Veratric Acid’s potential to scavenge free radicals makes it a candidate for use in formulations aimed at treating inflammatory conditions.
  • Organic Synthesis: As an intermediate in organic synthesis, Veratric Acid is employed in the production of more complex chemical compounds. Its structure allows for the introduction of additional functional groups, making it a versatile building block.
  • Natural Products Chemistry: Veratric Acid is studied for its role in the biosynthesis of plant-derived compounds. Its presence in natural products is often associated with potential health benefits, leading to its inclusion in nutraceuticals and herbal medicines.
  • Polymer Industry: In the polymer industry, Veratric Acid is sometimes used as a monomer or as a component in the production of biodegradable polymers, due to its natural origin and relatively low toxicity.

4. Synthesis and Derivatives

Veratric Acid can be synthesized through the methylation of vanillic acid or by demethylation of syringic acid. The availability of both methods provides flexibility in obtaining Veratric Acid for various research and industrial purposes. Derivatives of Veratric Acid, such as Veratryl Alcohol, are also important in the study of lignin biosynthesis and in various biochemical applications.

5. Safety and Handling

Veratric Acid is generally regarded as safe when handled properly, though it should still be managed with care in a laboratory or industrial setting. Proper personal protective equipment (PPE), such as gloves and safety glasses, should be used when handling the compound. It should be stored in a cool, dry place, away from incompatible materials such as strong oxidizing agents.

6. Safety Data

Hazard Classifications

  • Irritant: May cause irritation to the skin and eyes upon contact.
  • Environmental Hazard: Although not highly toxic, it should not be released into the environment without proper treatment.

Pictograms:

  • Exclamation Mark (Irritant)

Hazard Statements:

  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.

Precautionary Statements:

  • P280: Wear protective gloves, protective clothing, and eye protection.
  • P264: Wash hands thoroughly after handling.
  • P305+P351+P338: If in eyes, rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

7. Research and Studies

Recent research into Veratric Acid has explored its potential as an antioxidant and anti-inflammatory agent. Studies have indicated that Veratric Acid may help in the reduction of oxidative stress, making it a compound of interest in the development of treatments for various chronic conditions. Additionally, its role as an intermediate in the synthesis of other biologically active molecules has been extensively studied, highlighting its importance in medicinal chemistry.

Conclusion

Veratric Acid is a compound of significant interest in both industrial and research settings, particularly for its versatility in organic synthesis and potential health benefits. Understanding its properties, applications, and safety considerations is crucial for its effective use in various chemical processes. By adhering to proper safety protocols and utilizing Veratric Acid’s unique characteristics, this compound can be effectively integrated into numerous scientific and industrial applications.

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FAQ

What is the use of Veratric acid?

Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities.

What is 3 4 di methoxy benzoic acid?

Derivative of Protocatechuic Acid, and is a reagent used in the production of antimicrobial agents, antifeedants, and a variety of other biologically active compounds.

What is Acetoxybenzoic acid?

Acetoxybenzoic acid is the chemical name of aspirin. Aspirin is a commonly used antipyretic medicine i.e. medicine to lower the fever.

What is acid used for?

cids are often used to remove rust and other corrosion from metals in a process known as pickling

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