Overview
4-Hydroxy benzaldehyde, also known as p-hydroxy benzaldehyde, is an organic compound commonly used in the synthesis of pharmaceuticals, agrochemicals, and as an intermediate in various chemical processes. Known for its aromatic properties, this compound plays a significant role in both industrial applications and academic research. This post provides a detailed overview of 4-Hydroxy benzaldehyde, including its chemical properties, applications, and safety measures.
Description
4-Hydroxy benzaldehyde is a white to pale yellow crystalline powder with a characteristic almond-like odor. It is an aromatic aldehyde with a hydroxyl group attached to the benzene ring, which influences its reactivity and applications in organic synthesis.
Product Information
- IUPAC Name: 4-Hydroxy benzaldehyde
- Common Name: p-Hydroxy benzaldehyde
- CAS Number: 123-08-0
- Molecular Formula: C₇H₆O₂
- Molecular Weight: 122.12 g/mol
- Appearance: White to pale yellow crystalline powder
- Melting Point: 115-118°C
- Boiling Point: 191°C (at 760 mmHg)
- Solubility: Slightly soluble in water; soluble in organic solvents such as ethanol, ether, and benzene
Applications
- Pharmaceuticals
- 4-Hydroxy benzaldehyde is used as an intermediate in the synthesis of various pharmaceutical compounds, including anti-inflammatory and anti-microbial agents.
- Agrochemicals
- It serves as a precursor in the production of herbicides, fungicides, and other agrochemicals, contributing to improved agricultural productivity.
- Organic Synthesis
- Widely utilized in organic synthesis for the preparation of aromatic compounds, dyes, and fragrances due to its reactivity and aromatic properties.
- Research and Development
- Employed in academic and industrial research for studying reaction mechanisms and developing new synthetic methodologies.
Physicochemical Information
- Molecular Formula: C₇H₆O₂
- Molecular Weight: 122.12 g/mol
- Appearance: White to pale yellow crystalline powder
- Melting Point: 115-118°C
- Boiling Point: 191°C (at 760 mmHg)
- Solubility: Slightly soluble in water; soluble in organic solvents like ethanol, ether, and benzene
Safety Information According to GHS
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Hazard Statements:
- H302: Harmful if swallowed
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
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Precautionary Statements:
- P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
- P280: Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
- P302+P352: IF ON SKIN: Wash with plenty of soap and water.
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Safety Information
- Hazards: 4-Hydroxy benzaldehyde can cause irritation to the skin, eyes, and respiratory system. It is harmful if swallowed and should be handled with care to avoid exposure.
- Protective Measures: Use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work with 4-Hydroxy benzaldehyde should be conducted in a well-ventilated area, preferably in a fume hood.
- Storage: Store in tightly sealed containers, away from light, moisture, and incompatible substances.
Storage and Shipping Information
- Storage Conditions: Store in a cool, dry place in tightly sealed containers. Protect from light and moisture.
- Shipping Information: Transport according to local regulations. Ensure containers are secure and upright during transit to prevent leaks.
Transport Information
- UN Number: Not classified as hazardous for transport
- Hazard Class: Not classified
- Packing Group: Not classified
- Proper Shipping Name: Not classified
Specifications
- Purity: Typically >98%
- Appearance: White to pale yellow crystalline powder
- Melting Point: 115-118°C
- Boiling Point: 191°C (at 760 mmHg)
Related Products & Applications In Ketone Pharma
- 4-Hydroxybenzyl Alcohol: Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.
- 4-Hydroxybenzoic Acid: Employed in the production of preservatives, pharmaceuticals, and polymers.
- Vanillin: A flavoring agent derived from 4-hydroxy benzaldehyde.
- Phenolic Compounds: Various compounds used in the production of resins, plastics, and pharmaceuticals.
By understanding the chemical properties, applications, and safety measures of 4-Hydroxy benzaldehyde, researchers and industry professionals can effectively utilize this versatile compound in various scientific and industrial processes while ensuring safety and regulatory compliance.